By Edited by: Daniel L. Purich, Daniel L. Purich
This e-book is an element A in a subseries entitled "Amino Acid Metabolism". issues partially A may be of rapid curiosity to people who are generally considering amino acid assimilation and metabolism. Investigators drawn to enzyme mechanism and rules also will locate this quantity specifically useful.
Read Online or Download Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology PDF
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Extra info for Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology
J. Biol. , 209, 265-269 (1954). Liaw, S. , and Eisenberg, D. , 4, 2358-2365 (1995). Liaw, S. , and Eisenberg, D. , Proc. Natl. Acad. Sci. USA, 90, 4996-5000 (1993). Liaw, S. , Biochemistry, 33, 11184-11188 (1994). , Curr. Top. Cell. , 27, 215-220 (1985). Manning, J. , Rowe, W. , Biochemistry, 8, 2681-2685 (1%9). 42 DANIEL L. PURICH Mathews, C. K. and van Holde, K. , Benjamin-Cummings, Menlo Park, CA, 19%, p. 707. Meister, A. , Boyer, P. , and Myrback, K. , Vol. 6, 1962, pp. 443-468. , Adv. Enzymol.
Biochem. , 49, 106-112 (1951). , Park, I. , Walsh, C. , and Knox, J. , Biochemistry, 36, 2531-2538 (1997). , Atkinson, M. , Stock, J. , Wanner, B. , and Ninfa, A. , J . , 174, 6061-6070 (1992). Gass, J. , Biochemistry, 9, 1380-1388. Ginsburg, Biochemistry, 8, 1726-1734 (1%9). Hunt, J. , Smymiotis, P. , Ginsburg, A, and Stadtman, E. , Arch. Biochem. , 166, 102-124 (1975). Kamberov, E. , Atkinson, M. , and Ninfa, A. , Cell. Mol. Biol. , 40, 175-191 (1994). Kamberov, E. , Atkinson, M. , and Ninfa, A.
The basic hypothesis was that this enzyme, which itself catalyzes the fust committed step in the multipathway synthesis of nitrogen-containing end-products, was subject to cumulative feedback inhibition (Woolfolk and Stadtman, 1967). Such regulatory behavior would allow feedback inhibitors to throttle the en- ADVANCES IN THE ENZYMOLOGY OF GLUTAMINE SYNTHESIS 33 zyme’s catalytic activity without completely arresting glutamine biosynthesis, unless all of the end-products reached saturating concentrations.
Amino Acid Metabolism, Part A, Volume 72, Advances in Enzymology and Related Areas of Molecular Biology by Edited by: Daniel L. Purich, Daniel L. Purich