Read e-book online Animal Cell Culture and Production of Biologicals: PDF

By Teruhiko Beppu, Minoru Yoshida (auth.), Ryuzo Sasaki, Koji Ikura (eds.)

ISBN-10: 9401055726

ISBN-13: 9789401055727

ISBN-10: 9401135509

ISBN-13: 9789401135504

In the prior 20 years, the significance of animal telephone expertise has elevated tremendously. First, invaluable proteins could be produced by means of cultured animal cells, within which the specified product will be transformed and arranged with a view to hold its organic functionality. moment, stories of cultured cells delivers info had to comprehend molecular mechanisms that govern what occurs in tissues, organs, or even whole organisms. For this moment objective, biochemists and molecular biologists might have loads of such cells. 3rd, cultured cells can be utilized rather than tissues and organs clinically. The 3rd Annual assembly of the japanese organization for Animal mobile know-how (JAACT), at which individuals from overseas have been warmly welcomed, was once held in Kyoto on December 11-13, 1990. It used to be prepared round the thought of delivering a spot for the evaluate of a lot new information on such purposes of cultured cells and for exchanges of the perspectives of the individuals approximately growth within the box. This quantity, divided into seven sections, includes the lawsuits of the assembly. the 1st part stories the molecular foundation of the regulate of animal phone development. within the following sections, physicochemical and biochemical elements for cellphone progress and construction of biologicals, mobilephone tradition platforms together with serum-free tradition, new phone strains, particular items and their features, and in vitro assays for poisonous, carcinogenic, and pharmacological results are taken up of their tum.

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Additional info for Animal Cell Culture and Production of Biologicals: Proceedings of the Third Annual Meeting of the Japanese Association for Animal Cell Technology, held in Kyoto, December 11–13, 1990

Example text

CCL 171) (MRC-5) is important to enhance efficiency in lymphoblast culture initiation. Literally hundreds of human lymphoblastic lines have been developed at the ATCC using this procedure over the past two years. 3. Recent Acquisitions The majority of cell lines added to The Collection have been developed elsewhere. They are made available through the generosity of numerous originators, most of whom supply their material without charge and with minimal restrictions on distribution. A listing of selected cell lines added recently is provided in Table 2.

1985; Gazdar, et 32 TABLE 2. Recent additions to the ATCC cell repository* ATCC No. { assays carcinoma Lung Supports HBV carcinoma replication Gastric CEA & Mucin carcinoma positive Melanoma Assay for IL-1 Axillar Hyperdiploid sarcoma ChondroHyperdiploid sarcoma Thyroid Grade III giant cell tumor Vulva Lymph node metastasis Small cell Positive for carcinoma enolase and creatine kinase Papillary Lamellar bodies lung adeno- Surfactant carcinoma proteins AB & C Squamous Keratin and lung vimentin positive carcinoma Small cell Elevated levels carcinoma enolase, creatine kinase, dopa decarboxylase and bombesin MedulloUJ13A and blastoma enolase positive Thyroid carcinoma Colon Leong Thompson Holder Gazdar Shaver Newman Leibovitz Leibovitz Leibovitz Leibovitz Gazdar Gazdar Gazdar Gazdar Friedman 33 TABLE 2.

The latter involves greater risk of contamination, both from microorganisms and in the cell culture laboratory, and it puts greater pressure on recipients to coordinate their own laboratory work with the suppliers shipping schedule. In Japan ATCC cultures are distributed by Sumisho Pharma Corporation, 4-7-8 Kitahama chuo-ku, Osaka 541 and through The Japanese Cancer Research Resources Bank, Division of Genetics and Mutagenesis, National Institute of Hygienic Sciences, 1-18-1 Kami Yooga, Setagaya-ku, Tokyo 158.

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Animal Cell Culture and Production of Biologicals: Proceedings of the Third Annual Meeting of the Japanese Association for Animal Cell Technology, held in Kyoto, December 11–13, 1990 by Teruhiko Beppu, Minoru Yoshida (auth.), Ryuzo Sasaki, Koji Ikura (eds.)


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