Download e-book for kindle: Apoptosis, Cell Signaling, and Human Diseases: Molecular by Rakesh Srivastava

By Rakesh Srivastava

ISBN-10: 1588296776

ISBN-13: 9781588296771

ISBN-10: 1588298825

ISBN-13: 9781588298829

ISBN-10: 1597451991

ISBN-13: 9781597451994

(for either volumes) Apoptosis, mobilephone Signaling, and Human ailments: Molecular Mechanisms, Volumes 1 & 2, current a concise synthesis of contemporary advancements within the figuring out of either mobilephone survival and apoptotic pathways. specific cognizance is given to apoptosis in human illnesses, resembling varied varieties of melanoma and neurodegenerative illnesses. those accomplished volumes combine the main leading edge and present findings from a number of comparable disciplines of medical examine, together with pathology, genetics, virology, cellphone biology, immunology, and molecular biology. quantity 1 is split into sections: "Malignant Transformation and Metastasis" and "Molecular foundation of sickness Therapy." quantity 2 follows the same constitution and is split into sections entitled "Kinases and Phosphate" and "Molecular foundation of phone Death." all the individuals are on the vanguard of medical discovery, and the studies they current systemically learn the main interesting and leading edge elements in their specific components of craftsmanship. Researchers will locate those volumes of significant gain as they look for novel and better remedies for human illnesses.

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Extra info for Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms

Sample text

Monia BP, Lesnik EA, Gonzalez C, Lima WF, McGee D, Guinosso CJ, et al. Evaluation of 2e-modified oligonucleotides containing 2e-deoxygaps as antisense inhibitors of gene expression. J Biol Chem 1993;268:14,514–14,522. 137. Shibahara S, Mukai S, Morisawa H, Nakashima H, Kobayashi S, Yamamoto N. Inhibition of human immunodeficiency virus (HIV-1) replication by synthetic oligo-RNA derivatives. Nucleic Acids Res 1989;17:239–252. 138. Tortora G, Ciardiello F. Protein kinase A as target for novel integrated strategies of cancer therapy.

Whether alterations in PKC activity enhance or suppress apoptosis appears to depend on the initiating signal as well as the specific cell type.

Halgren RG, Traynor AE, Pillay S, et al. 8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine. Blood 1998; 92:2893–2898. 114. Tagliaferri P, Katsaros D, Clair T, et al. Synergistic inhibition of growth of breast and colon human cancer cell lines by site-selective cyclic AMP analogues. Cancer Res 1988;48: 1642–1650. 115. Koontz JW, Wicks WD. Cytotoxic effects of two novel 8-substituted cyclic nucleotide derivaties in cultured rat hepatoma cells.

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Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms by Rakesh Srivastava

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