By Hanjoong Jo, Ho-Wook Jun, Jennifer Shin, SangHoon Lee
This publication presents readers with an integrative assessment of the newest study and advancements within the wide box of biomedical engineering. all of the chapters deals a well timed evaluation written through top biomedical engineers and goals at displaying how the convergence of medical and engineering fields with medication has created a brand new foundation for essentially fixing difficulties pertaining to human health and wellbeing, health and affliction. whereas many of the most recent frontiers of biomedicine, corresponding to neuroscience and regenerative medication, have gotten more and more depending on new rules and instruments from different disciplines, the paradigm shift because of technological strategies within the fields of data technological know-how, nanotechnology, and robotics is beginning new possibilities in healthcare, along with dramatically altering the methods we really perform technology. while, a brand new new release of engineers, fluent in lots of assorted medical “languages,” is growing completely new fields of analysis that process the “old” questions from a brand new and holistic attitude. The publication studies at the clinical revolutions within the box of biomedicine through describing the most recent applied sciences and findings constructed on the interface among technological know-how and engineering. It addresses scholars, fellows, and college and investigators looking for new demanding situations within the wide biomedical engineering fields.
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Additional info for Biomedical Engineering: Frontier Research and Converging Technologies
J. Kim et al. studies in experimental models and clinical trials have demonstrated that islet transplantation represents an alternative approach to insulin therapy since islet transplantation provides a better normalization of metabolic control . For clinical islet transplantation, the procedure involves infusion of isolated islets in the liver via the portal vein. This procedure is relatively fast and safe, and can be performed under anesthesia. Even though significant improvements have been achieved in this area, many challenges are still present, such as preservation of islet function and improvement of islet engraftment .
Therefore, MRI is a powerful tool to monitor transplanted islets. Another alternative non-invasive imaging method is positron emission tomography (PET). PET is a nuclear medical imaging method used to evaluate the functional processes in the body. It has good sensitivity and high resolution. PET images are obtained by the cellular consumption of molecules that are labeled with positron-emitting isotopes. The first trial to detect islets used 2-[18F] fluoro-2deoxy-D-glucose (FDG) . FDG was internalized into the pancreatic islet via glucose transporters, thereby enabling labeling and imaging of islets.
J. Kim et al. 22. : Bcl-2functionalized ultrasmall superparamagnetic iron oxide nanoparticles coated with amphiphilic polymer enhance the labeling efficiency of islets for detection by magnetic resonance imaging. International Journal of Nanomedicine 8, 3977–3990 (2013) 23. : In vivo imaging of islet transplantation. Nature Medicine 12, 144–148 (2006) 24. : Liposome-Mediated Transfer Can Improve the Efficacy of Islet Labeling With Superparamagnetic Iron Oxide. Transpl P. 40, 3615–3618 (2008) 25.
Biomedical Engineering: Frontier Research and Converging Technologies by Hanjoong Jo, Ho-Wook Jun, Jennifer Shin, SangHoon Lee