Bioresorbable Polymers for Biomedical Applications. From - download pdf or read online

By Giuseppe Perale, Jöns Hilborn

ISBN-10: 0081002629

ISBN-13: 9780081002629

ISBN-10: 0081002661

ISBN-13: 9780081002667

Bioresorbable Polymers for Biomedical purposes: From basics to Translational Medicine offers readers with an summary of bioresorbable polymeric fabrics within the biomedical box. an invaluable source for fabrics scientists in and academia, providing info at the basics and issues, synthesis and processing, and the medical and R and D functions of bioresorbable polymers for biomedical applications.

  • Focuses on biomedical functions of bioresorbable polymers
  • Features a finished diversity of themes together with basics, synthesis, processing, and applications
  • Provides balanced insurance of the sphere with contributions from academia and industry
  • Includes medical and R and D purposes of bioresorbable polymers for biomedical applications

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Extra resources for Bioresorbable Polymers for Biomedical Applications. From Fundamentals to Translational Medicine

Example text

This is the major recognition system for cell adhesion (Yamamoto, 1995); therefore, the healing process is tremendously accelerated (Pertici, 2015). Permeability is well known as a limiting factor in common 24 Bioresorbable Polymers for Biomedical Applications procedures such as bone replacement by allograft substitutes (Toms, 2004). Moreover, the major risk in adopting cadaver-derived material is viral disease transmission and bacterial infection, especially when fresh grafts are performed. Recognized as “non-self,” the allograft is attacked by the immune system.

Another solution is the beta radiation (high-speed electrons), which is less aggressive than gamma radiation, but the kind of packaging limits this application due to the low penetration power. An alternative is the use of ethylene oxide gas, normally well tolerated by polymers. This technique is highly toxic, and it requires a long period of degassing and specific analysis to guarantee no residuals left inside the device. The biomedical industry is focusing interest on methods such as plasma and supercritical CO2 processing to obtain new sterilization technologies (Buchanan, 2008).

5 Coating, solvent casting, and foaming Often, the surface modification of biomedical devices is required to maximize performance. The surface can be modified in many ways, including plasma modification and application of coatings to the substrate. Surface modifications can be used to affect surface energy, cell adhesion, mechanical performance, chemical inertness, lubricity, degradation, bioactive agents release, and hydrophilicity. In general, the lower the surface tension of a liquid coating, the easier it will be to produce a satisfactory wet film from it.

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Bioresorbable Polymers for Biomedical Applications. From Fundamentals to Translational Medicine by Giuseppe Perale, Jöns Hilborn


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