Download PDF by Ahindra Nag: Computer-aided drug design and delivery systems

By Ahindra Nag

ISBN-10: 0071701249

ISBN-13: 9780071701242

ISBN-10: 0071701257

ISBN-13: 9780071701259

ISBN-10: 0071764275

ISBN-13: 9780071764278

ISBN-10: 7100701244

ISBN-13: 9787100701242

"This state-of-the-art quantity studies the most recent breakthroughs in CADD (Computer-Aided Drug Design), drug supply platforms, and permitting technologies"--Provided by means of publisher.

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Additional info for Computer-aided drug design and delivery systems

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8. Absence of problems. The IDDS reduces or causes no new problems or concerns. 9. Reliability. 10. Marketplace value. The IDDS offers high value by featuring maximum functionality at minimum complexity and cost. Advantages 1. Avoidance of presystemic metabolism 2. Reduction of intra- and interpatient variability 3. Maintenance of drug level in the systemic circulation within the therapeutic window 4. Extension of drug duration of action by a single administration thereby reducing the frequency of dosing Drug Delivery Systems 5.

Adsorption to the cell surface either by nonspecific weak hydrophobic or electrostatic forces or by specific interactions with cell surface components 3. Fusion with the plasma cell membrane by insertion of the lipid bilayer of the liposome into the plasma membrane, with simultaneous release of liposomal contents into the cytoplasm 4. Transfer of liposomal lipids to cellular or subcellular membranes without any association of the liposome contents Liposomes can be injected, and they persist in tissues for hours or days depending on their composition and half-lives in the blood.

A successful bioinformatics application implies functional correlation that assumes a similarity between two sequences, whether it is DNA, RNA, or protein. Functional genomics. This deals with calculation of the 3D structure of a macromolecule based on its sequence, providing the theoretical basis of relationships between sequences and structure, one of the most fundamental problems in in silico biology. It also deals with folding problems, a demanding objective of computational biology. Pharmacogenomics.

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Computer-aided drug design and delivery systems by Ahindra Nag

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