By Peter Koopman (Eds.)
ISBN-10: 0123809126
ISBN-13: 9780123809124
Knowing organogenesis is vital to present efforts to direct stem mobilephone differentiation and serve as within the context of a fancy organ. Defects in organogenesis are frequently the main manifestations of human genetic disorder syndromes. This quantity describes the advance of 10 significant organ platforms, reviewed by way of specialists in each one, to supply an updated evaluate for researchers inside and outdoors the sphere, scholars, lecturers and clinicians. Summarizes the most important morphological and mobile occasions Emphasizes up to date study on the subject of molecular keep an eye on mechanisms attracts on various version vertebrates and modern experimental ways, together with classes learnt from human developmental ailment Distils universal subject matters and changes for comparative experiences Highlights key ultimate questions and units the schedule for destiny examine
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Murphy, T. , Langer, E. , Nerbonne, J. , Kyba, M. and Murphy, K. M. (2008). Mesp1 coordinately regulates cardiovascular fate restriction and epithelial–mesenchymal transition in differentiating ESCs.
2006). Cardiac arterial pole alignment is sensitive to FGF8 signaling in the pharynx. Dev. Biol. 295, 486–497. , Terrell, P. and Baldini, A. (2007). A fate map of tbx1 expressing cells reveals heterogeneity in the second cardiac field. Genesis 45, 470–475. , Schwartz, R. , Klingensmith, J. and Meyers, E. N. (2006). Fgf8 is required for anterior heart field development. Development 133, 2435–2445. 34 Ste´phane D. Vincent and Margaret E. , Ataliotis, P. and Scambler, P. J. (2005). Microarray analysis detects differentially expressed genes in the pharyngeal region of mice lacking tbx1.
Johnson, G. , Meyers, E. N. and Klingensmith, J. (2008). Intracardiac septation requires hedgehog-dependent cellular contributions from outside the heart. Development 135, 1887–1895. Goddeeris, M. , Klingensmith, J. and Meyers, E. N. (2007). Independent requirements for hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development. Development 134, 1593–1604. Guris, D. , Papaioannou, V. E. and Imamoto, A. (2006). Dose-dependent interaction of tbx1 and crkl and locally aberrant RA signaling in a model of del22q11 syndrome.
Organogenesis in Development by Peter Koopman (Eds.)
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