The design and manufacture of medical devices - download pdf or read online

By edited by J. Paulo Davim.

ISBN-10: 1907568727

ISBN-13: 9781907568725

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2 Haemocompatibility The haemocompatibility of the implant material is closely related to the reactions between the surface of the biomaterial and the inflammatory host response (Teo, 2000). , 1997). The human body has the ability to resist attack from foreign materials. When the foreign surface of a biomaterial is placed in contact with blood, it activates a number of plasma enzymes and several complicated reactions then occur. 1). Adherent platelets chemically signal circulating platelets that promote additional platelet adhesion, activation and aggregation.

Next, in the electron transfer process, an electron jumps from an occupied orbital of the donor reactant at ground state (D) to the empty orbital of the acceptor reactant at excited state (A*). The electron transfer process requires the overlap between the occupied donor orbital and the empty or half-filled acceptor orbital (Banerjee, 2011). , 2008). An application that has attracted considerable attention is the use of titanium oxide (TiO2) photocatalysts, as an alternative material to aid in the purification of water and air.

Implanted titanium dioxide has been found to absorb different amounts of human albumin and fibrinogen and adhering platelets. , 2001). It has been suggested that proteins are adsorbed chemically onto the surface oxide layer of a titanium implant through the interaction of carbon and oxygen groups. , 2003). , 2010). 1 Photocatalytic activity TiO2 is used for photocatalysis due to its inertness, chemical stability, low cost and high reactivity under UV light irradiation (λ > 390 nm] (Mills and Hunte, 1997).

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The design and manufacture of medical devices by edited by J. Paulo Davim.


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