Viral nanotechnology by Yury Khudyakov, Paul Pumpens PDF

By Yury Khudyakov, Paul Pumpens

ISBN-10: 1466583533

ISBN-13: 9781466583535

Viral Nanotechnology provides an up to date evaluation of the quickly constructing box of viral nanotechnology within the parts of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Its chapters are via major researchers and practitioners, making it either a accomplished and vital source for examine and research.

The box of viral nanotechnology is new and fast increasing as a result of expanding call for of the functions already constructed. The editors determine viral nanotechnology as an important technological know-how that issues itself with how one can use the molecular modules that the exceedingly assorted technological know-how of molecular engineering in simple terms constructs. the present strength functions of viral know-how are manifold, with possibilities to revolutionize practices in photonics, catalysis, electronics, power, biomedicine, healthiness care, and public health.

This booklet emphasizes utilizing viral nanotechnology to enhance healthiness. a unique emphasis is put upon utilizing viral nanotechnology for constructing vaccines. moreover, it records viral nanotechnology’s use as a robust device for constructing medicinal drugs and genetic treatments. there's additionally nice strength in its use as a method for diagnostics, together with the improvement of diagnostic reagents and novel imaging applied sciences for detecting affliction and infectious agents.

Viral nanotechnology’s fast and intriguing progress is because of the necessity for brand new instruments within the prevention, analysis, and therapy of illness. The individuals to this quantity technique every one bankruptcy with the wish that their learn and practices will give a contribution to an development in wellbeing and fitness and lifestyles on an unparalleled scale in human history.

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Viral nanotechnology - download pdf or read online

Viral Nanotechnology provides an updated review of the swiftly constructing box of viral nanotechnology within the parts of immunology, virology, microbiology, chemistry, physics, and mathematical modeling. Its chapters are via best researchers and practitioners, making it either a complete and critical source for examine and study.

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Science, 1986. 231(4744): 1401–1406. Tang, J. , Molecular links between the E2 envelope ­glycoprotein and nucleocapsid core in Sindbis virus. J Mol Biol, 2011. 414(3): 442–459. 32. Sun, S. , Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization. Elife (Cambridge), 2013. 2: e00435. Zhang, R. 4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. EMBO J, 2011. 30(18): 3854–3863. Li, L. , The flavivirus precursor membrane-envelope protein complex: Structure and maturation.

Scaffold is flexible protein that binds relatively weakly to capsid via electrostatic interactions [119,123]. In vitro, excess scaffold leads to many incomplete capsids, exactly analogous to the kinetic traps achieved with homopolymer capsid assembly [119,121]. Because scaffold participation is nonstoichiometric, appropriate assembly models must correlate changes in capsid stability with the amount of scaffold [121,186]. A straightforward binding analysis shows the linkage between assembly and scaffold concentration [186].

J Mol Biol, 1999. 288(4): 595–608. D. , Structure and size determination of ­bacteriophage P2 and P4 procapsids: Function of size responsiveness mutations. J Struct Biol, 2012. 178(3): 215–224. 11 28. Zheng, W. J. Tao, Structure and assembly of the influenza A virus ribonucleoprotein complex. FEBS Lett, 2013. 587(8): 1206–1214. 29. A. , Crystal structure of the rabies virus nucleoprotein–RNA complex. Science, 2006. 313(5785): 360–363. 30. Namba, K. and G. 6 Å resolution: Implications for assembly.

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Viral nanotechnology by Yury Khudyakov, Paul Pumpens

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